83. Acute copper oxide nanoparticles exposure alters zebrafish larval microbiome

Life Sciences

Satheeswaran Balasubramanian, Mariam Azeezuddin Haneen, Gaurav Sharma, Ekambaram Perumal

82. Natural bioactive compounds and STAT3 against hepatocellular carcinoma: An update

Life sciences

Suryaa Manoharan, Shreejit Saha, Krishnasanthiya Murugesan, Aksayakeerthana Santhakumar, Ekambaram Perumal

81. Angiogenesis Assay for Live and Fixed Zebrafish Embryos/Larvae

Teratogenicity Testing: Methods and Protocols

S Vinoth, Satheeswaran Balasubramanian, Ekambaram Perumal, Kirankumar Santhakumar

80. Natural bioactive compounds and FOXO3a in cancer therapeutics: an update

Fitoterapia

Suryaa Manoharan, Kunjkumar Prajapati, Ekambaram Perumal

79. MAO inhibiting phytochemicals from the roots of Glycyrrhiza glabra L.

Journal of Biomolecular Structure and Dynamics

Monojit Bhattacharjee, Suryaa Manoharan, Umamaheswari Sathisaran, Anand Tamatam, Ekambaram Perumal

78. Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach

Cancer Biomarkers

S Vinoth, Satheeswaran Balasubramanian, Ekambaram Perumal, Kirankumar Santhakumar

77. Virtual screening of FOXO3a activators from natural product-like compound library

Molecular Diversity

Suryaa Manoharan, Kunjkumar Prajapati, Tharini Karthikeyan, Hemamalini Vedagiri, Ekambaram Perumal

76. MicroRNAs in fluorosis pathogenesis: impact on dental, skeletal, and soft tissues

Archives of Toxicology

Suryaa Manoharan, Syed Saadullah Ashfaq, Ekambaram Perumal

75. Neurobehavioral effects of nanoparticles in zebrafish: a systematic review and meta-analysis

OSF

Satheeswaran Balasubramanian, Ekambaram Perumal

74. A strategic review of STAT3 signaling inhibition by phytochemicals for cancer prevention and treatment: Advances and insights

Fitoterapia

Suryaa Manoharan, Ekambaram Perumal

73. Targeting STAT3, FOXO3a, and Pim-1 kinase by FDA-approved tyrosine kinase inhibitor-Radotinib: An in silico and in vitro approach

Archiv der Pharmazie

Suryaa Manoharan, Aksayakeerthana Santhakumar, Ekambaram Perumal

72. Integrated in silico analysis of transcriptomic alterations in nanoparticle toxicity across human and mouse models

Science of The Total Environment

Satheeswaran Balasubramanian, Ekambaram Perumal

71. Early-stage biomarkers identification by integrated genomic analysis in hepatocellular carcinoma

Medicine in Omics

Suryaa Manoharan, Ekambaram Perumal

70. A comprehensive review of targeting early-stage biomarkers by small molecules and phytochemicals in hepatocellular carcinoma

Phytochemistry Reviews

S Manoharan, I Govindaraju, V Venkatesan, E Perumal

69. Fluoride induced neurobehavioral impairments in experimental animals: a brief review

Biological Trace Element Research

Harsheema Ottappilakkil, Srija Babu, Satheeswaran Balasubramanian, Suryaa Manoharan, Ekambaram Perumal

68. Acute hypobaric hypoxia exposure causes neurobehavioral impairments in rats: role of brain catecholamines and tetrahydrobiopterin alterations

Neurochemical Research

Monojit Bhattacharjee, Suryaa Manoharan, Uma Maheswari Deshetty, Ekambaram Perumal

67. Toxicogenomic analysis of physiologically important metals: An integrated in silico approach

Food and Chemical Toxicology

Satheeswaran Balasubramanian, Vaishnavi Duraikannan, Ekambaram Perumal

66. Fluoride Binding Potential of Selected Phytochemicals: A Pilot Study

Environmental Science and Pollution Research

Harsheema Ottappilakkil, Anitha Ottoor, Suryaa Manoharan, Murugesapandian Balasubramanian, Ekambaram Perumal

65. Screening of potent STAT3‐SH2 domain inhibitors from JAK/STAT compound library through molecular dynamics simulation

Molecular Diversity

Suryaa Manoharan, Ajithkumar Balakrishnan, Vedagiri Hemamalini, Ekambaram Perumal

64. Role of oxidative stress-mediated cell death and signaling pathways in experimental fluorosis

Chemico-Biological Interactions

Srija Babu, Suryaa Manoharan, Harsheema Ottappilakkil, Ekambaram Perumal

63. A systematic review on fluoride-induced epigenetic toxicity in mammals

Critical Reviews in Toxicology

Satheeswaran Balasubramanian, Ekambaram Perumal

62. Potential role of marine bioactive compounds in cancer signaling pathways: A review

European Journal of Pharmacology

Suryaa Manoharan, Ekambaram Perumal

61. Chemotherapeutic Potential of Saikosaponin D: Experimental Evidence

Journal of Xenobiotics

Suryaa Manoharan, Bhuvaneshwari Deivendran, Ekambaram Perumal

60. Mitigation of arsenic induced developmental cardiotoxicity by ferulic acid in zebrafish

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology

Ekambaram Perumal, Sangavi Eswaran, Reshma Parvin, Satheeswaran Balasubramanian

59. Evaluation of Maghemite Nanoparticles–Induced Developmental Toxicity and Oxidative Stress in Zebrafsh Embryos/Larvae

Biological Trace Elements Research

Naveenkumar Anaimalai Thirumurthi, Azhwar Raghunath, Satheeswaran Balasubramanian, Ekambaram Perumal

58. Integrated in silico analysis for the identification of key genes and signaling pathways in copper oxide nanoparticles toxicity

Toxicology

Satheeswaran Balasubramanian, Ekambaram Perumal

57. Fisetin inhibits autophagy in HepG2 cells via PI3K/Akt/mTOR and AMPK pathway

Nutrition and cance

Kiruthika Sundarraj, Azhwar Raghunath, Lakshmikanthan Panneerselvam, Ekambaram Perumal

56. Chronic exposure to copper oxide nanoparticles causes muscle toxicity in adult zebrafish

Environmental Science and Pollution Research

Ramya Mani, Satheeswaran Balasubramanian, Azhwar Raghunath, Ekambaram Perumal

55. Ferulic Acid Attenuates Arsenic Induced Cardiotoxicity in Rats

Biotechnology and Applied Biochemistry

L Panneerselvam, A Raghunath, MS Ravi, A Vetrivel, V Subramaniam, K Sundarraj, E Perumal

54. Fisetin, a phytopolyphenol, targets apoptotic and necroptotic cell death in HepG2 cells

Biofactors

K Sundarraj, A Raghunath, L Panneerselvam, E Perumal

53. Ameliorative Effect of Hesperidin Against Motion Sickness by Modulating Histamine and Histamine H1 Receptor Expression

Neurochemical Research

Uma Maheshwari Deshetty, Anand Tamatam, Monojit Bhattacharjee, Ekambaram Perumal, Gopalan Natarajan, Farhath Khanum

52. Selective detection of pyrophosphate anion by zinc ensemble of C3-symmetric triaminoguanidine-pyrrole conjugate and its biosensing applications

Analytica Chimica Acta

Balamurugan Tharmalingam, Moorthy Mathivanan, Kailasam Saravana Mani, Werner Kaminsky, Azhwar Raghunath, Mathivanan Jothi, Ekambaram Perumal, Balasubramanian Murugesapandian

51. ZFARED: A Database of the Antioxidant Response Elements in zebrafish

Current Bioinformatics

Azhwar Raghunath, Raju Nagarajan, Ekambaram Perumal

50. MicroRNAs and Xenobiotic Toxicity: An Overview

Toxicology Reports

Satheeswaran Balasubramanian, Kanmani Gunasekaran, Saranyadevi Sasidharan, Vignesh Jeyamanickavel Mathan, Ekambaram Perumal

49. Chitosan-coated silver nanoparticles promoted antibacterial, antibiofilm, wound-healing of murine macrophages and antiproliferation of human breast cancer MCF 7 cells

Polymer Testing

Ayyanar Parthasarathy, Sekar Vijayakumar, Balasubramanian Malaikozhundan, Merlin P Thangaraj, Perumal Ekambaram, Thangaswamy Murugan, Palaniyandi Velusamy, Periasamy Anbu, Baskaralingam Vaseeharan

48. Acute fluoride exposure alters myocardial redox and inflammatory markers in rats

Molecular Biology Reports

L Panneerselvam, A Raghunath, K Sundarraj, E Perumal

47. Role of epigenetics in zebrafish development

Gene

Satheeswaran Balasubramanian, Azhwar Raghunath, Ekambaram Perumal

46. HO-1/HSP32 and Cardiac Stress Signaling

Heat Shock Proteins in Signaling Pathways. Heat Shock Proteins,

Lakshmikanthan Panneerselvam, Azhwar Raghunath, Kiruthika Sundarraj, Ekambaram Perumal

45. Iron Oxide Nanoparticles Affects Behaviour and Monoamine Levels in Mice

Neurochemical Research

Vijayprakash Manickam, Vasanth Dhakshinamoorthy, Ekambaram Perumal

44. Identification of compounds that inhibit the binding of Keap1a/Keap1b Kelch DGR domain with Nrf2 ETGE/DLG motifs in zebrafish

Basic & clinical pharmacology & toxicology

Azhwar Raghunath, Raju Nagarajan, Kiruthika Sundarraj, Kavipriya Palanisamy, Ekambaram Perumal

43. Potential plant-derived catecholaminergic activity enhancers for neuropharmacological approaches: A Review

Phytomedicine

Monojit Bhattacharjee, Ekambaram Perumal

42. Dysregulation of Nrf2 in Hepatocellular Carcinoma: Role in Cancer Progression and Chemoresistance

Cancers

Azhwar Raghunath, Kiruthika Sundarraj, Arfuso Frank, Gowtam Sethi, Ekambaram Perumal

41. Genome-wide identification and analysis of Nrf2 binding sites–Antioxidant response elements in zebrafish

Toxicology and Applied Pharmacology

Azhwar Raghunath, Raju Nagarajan, Kiruthika Sundarraj, Lakshmikanthan Panneerselvam, Ekambaram Perumal

40. Tamarind seed coat extract restores fluoride-induced hematological and biochemical alterations in rats

Environmental Science and Pollution Research

Jaishabanu Ameeramja, Azhwar Raghunath, Ekambaram Perumal

39. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats

Food and Chemical Toxicology

Jaishabanu Ameeramja, Vishnu Vignesh Kanagaraj, Ekambaram Perumal

38. Possible modulatory effect of tamarind seed coat extract on fluoride-induced pulmonary inflammation and fibrosis in rats

Inflammation

Jaishabanu Ameeramja, Ekambaram Perumal

37. Plant Sources as Potential Therapeutics for Alzheimer’s Disease

Medicinal Plants: Promising Future for Health and New Drugs

Azhwar Raghunath, Kiruthika Sundarraj, Vishnu Vignesh Kanagaraj, Ekambaram Perumal

36. Iron oxide nanoparticles induces cell cycle-dependent neuronal apoptosis in mice

Journal of Molecular Neuroscience

Vijayprakash Manickam, Vasanth Dhakshinamoorthy, Ekambaram Perumal

35. Antioxidant response elements: discovery, classes, regulation and potential applications

Redox biology

Azhwar Raghunath, Kiruthika Sundarraj, Raju Nagarajan, Frank Arfuso, Bian Jinsong, Alan P Kumar, Gautam Sethi, Ekambaram Perumal

34. A review on the chemotherapeutic potential of fisetin: In vitro evidences

Biomedicine & Pharmacotherapy

Kiruthika Sundarraj, Azhwar Raghunath, Ekambaram Perumal

33. Recurrent exposure to ferric oxide nanoparticles alters myocardial oxidative stress, apoptosis and necrotic markers in male mice

Chemico-biological interactions

Vijayprakash Manickam, Madhivadhani Periyasamy, Vasanth Dhakshinamoorthy, Lakshmikanthan Panneerselvam, Ekambaram Perumal

32. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells

Food and Chemical Toxicology

Jaishabanu Ameeramja, Ekambaram Perumal

31. Pulmonary fluorosis: a review

Environmental Science and Pollution Research

Jaishabanu Ameeramja, Ekambaram Perumal

30. Differential expression of myocardial heat shock proteins in rats acutely exposed to fluoride

Cell Stress and Chaperones

Lakshmikanthan Panneerselvam, Azhwar Raghunath, Ekambaram Perumal

29. Neurobehavioural toxicity of iron oxide nanoparticles in mice

Vasanth Dhakshinamoorthy, Vijayprakash Manickam, Ekambaram Perumal

Neurotoxicity research

28. Iron oxide nanoparticles modulate heat shock proteins and organ specific markers expression in mice male accessory organs

Toxicology and applied pharmacology

Kiruthika Sundarraj, Azhwar Raghunath, Lakshmikanthan Panneerselvam, Ekambaram Perumal

27. Aruljothi Subramaniam, Kiruthika Sundarraj, Azhwar Raghunath, Ekambaram Perumal

International Journal of Cardiology

Lakshmikanthan Panneerselvam, Azhwar Raghunath, Ekambaram Perumal

26. Metal oxide nanoparticles as antimicrobial agents: a promise for the future

International journal of antimicrobial agents

Azhwar Raghunath, Ekambaram Perumal

25. Repeated exposure to iron oxide nanoparticles causes testicular toxicity in mice

Environmental toxicology

Kiruthika Sundarraj, Vijayprakash Manickam, Azhwar Raghunath, Madhivadhani Periyasamy, Mangala Priya Viswanathan, Ekambaram Peruma

24. Therapeutic effects of gold nanoparticles synthesized using Musa paradisiaca peel extract against multiple antibiotic resistant Enterococcus faecalis biofilms and human lung cancer cells (A549)

Microbial pathogenesis

Sekar Vijayakumar, Baskaralingam Vaseeharan, Balasubramanian Malaikozhundan, Narayanan Gopi, Perumal Ekambaram, R Pachaiappan, Palaniyandi Velusamy, K Murugan, G Benelli, R Suresh Kumar, M Suriyanarayanamoorthy

23. In silico prediction of microRNAs on fluoride induced sperm toxicity in mice

Food and Chemical Toxicology

Azhwar Raghunath, Dhivyalakshmi Jeyabaskar, Kiruthika Sundarraj, Lakshmikanthan Panneerselvam, Ekambaram Perumal

22. Acute and sub‐lethal exposure to copper oxide nanoparticles causes oxidative stress and teratogenicity in zebrafish embryos

Journal of Applied Toxicology

Santhanamari Ganesan, Naveenkumar Anaimalai Thirumurthi, Azhwar Raghunath, Savitha Vijayakumar, Ekambaram Perumal

21. Antibacterial, antibiofilm and cytotoxic effects of Nigella sativa essential oil coated gold nanoparticles

Microbial pathogenesis

Sivalingam Manju, Balasubramanian Malaikozhundan, Sekar Vijayakumar, Sathappan Shanthi, Ameeramja Jaishabanu, Perumal Ekambaram, Baskaralingam Vaseeharan

20. Tamarind seed coat ameliorates fluoride induced cytotoxicity, oxidative stress, mitochondrial dysfunction and apoptosis in A549 cells

Journal of hazardous materials

Jaishabanu Ameeramja, Lakshmikanthan Panneerselvam, Vimal Govindarajan, Sivakamavalli Jeyachandran, Vaseeharan Baskaralingam, Ekambaram Perumal

19. Single oral acute fluoride exposure causes changes in cardiac expression of oxidant and antioxidant enzymes, apoptotic and necrotic markers in male rats

Biochimie

Lakshmikanthan Panneerselvam, Vimal Govindarajan, Jaishabanu Ameeramja, Harikumaran Raveendran Nair, Ekambaram Perumal

18. Micro-RNAs and their roles in eye disorders

Ophthalmic research

Azhwar Raghunath, Ekambaram Perumal

17. Caffeic acid, a phyto polyphenol mitigates fluoride induced hepatotoxicity in rats: a possible mechanism

Biofactors

Vishnu Vignesh Kanagaraj, Lakshmikanthan Panneerselvam, Vimal Govindarajan, Jaishabanu Ameeramja, Ekambaram Perumal

16. Acute exposure to titanium dioxide (TiO2) induces oxidative stress in zebrafish gill tissues

Toxicological & Environmental Chemistry

Sujatha Purushothaman, Azhwar Raghunath, Vasanth Dhakshinamoorthy, Lakshmikanthan Panneerselvam, Ekambaram Perumal

15. An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Apoptosis

Aruljothi Subramaniam, Ser Yue Loo, Peramaiyan Rajendran, Kanjoormana A Manu, Ekambaram Perumal, Feng Li, Muthu K Shanmugam, Kodappully Sivaraman Siveen, Joo-In Park, Kwang Seok Ahn, Kam M Hui, Alan P Kumar, Gautam Sethi

14. Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

PloS one

Kanjoormana Aryan Manu, Muthu K Shanmugam, Tina H Ong, Aruljothi Subramaniam, Kodappully Sivaraman Siveen, Ekambaram Perumal, Ramar Perumal Samy, Pradeep Bist, Lina HK Lim, Alan Prem Kumar, Kam M Hui, Gautam Sethi

13. Potential role of signal transducer and activator of transcription (STAT) 3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma

Biochimica et biophysica acta (BBA)-Reviews on Cancer

Nachiyappan, Xiaoyun Dai, Shivananju Nanjunda Swamy, Kwang Seok Ahn, Alan Prem Kumar, Benny KH Tan, Kam Man Hui, Gautam Sethi

12. Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

British Journal of Pharmacology

Aruljothi, S., Muthu, K.S., Tina, H.O., Feng, L., Perumal E, Luxi, C., Shireen, V., Taher, A., Shweta, K., Kwang, S.A., Alan, P.K., Kam, M.H. and Gautam, S

11. Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthoptic model of human hepatocellular carcinoma

PLoS One

Manu, K.A., Shanmugam, M.K., Ong, T.H., Aruljothi, S., Siveen, K.S., Perumal E, Samy, R.P., Bist,P. Lim, L.H., Kumar, A.P., Hui, K.M. and Sethi, G

10. A brief review on experimental fluorosis

Toxicology Letters

Perumal E, Vanaja, P., Vimal, G. and Lakshmikanthan, P

9. Potential role of signal transducer and activator of transcription (STAT3) singaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma

Biochim Biphys Acta

Aruljothi, S., Shanmugam, M.K., Perumal E, Li, F., Nachiyappan, A., Dai, X., Swamy, S.N., Ahn, K.S., Kumar, A.P., Tan, B.K., Hui, K.M. and Sethi, G

8. Therapeutic efficacy of Tamarindus indica (L) to protect against fluoride-induced oxidative stress in the liver of female rats

Fluoride

Perumal E, Namitha, T., Bhuvaneswari, S., Aruljothi, S., Vasanth, D. and Saravanakumar, M

7. Effects of sodium nitroprusside, a nitric oxide donor, on gamma-aminobutyric acid concentration in the brain and on picrotoxin-induced convulsions in combination with phenobarbitone in rats

Pharmacology Biochemistry and Behavior

Paul, V. and Perumal E

6. Demonstrating the dose- and time-related effects of 7 nitroindazole on picrotoxin-induced convulsion, memory formation, brain nitric oxide synthase activity, and nitric oxide concentration in rats

Pharmacology Biochemistry and Behavior

Vanaja, P. and Perumal E

5. Effect of vitamin D on chronic behavioural and dental toxicities of sodium fluoride in rats

Fluoride

Perumal E. and Paul, V

4. Prevention of picrotoxin convulsions-induced learning and memory impairment by nitric oxide increasing dose of L-arginine in rats

Pharmacology Biochemistry and Behavior

Paul, V., Reddy, L., & Perumal E

3. Modulation of fluoride in rats by calcium carbonate and by withdrawal of fluoride exposure

Pharmacology and Toxicology

Perumal E. and Paul, V.

2. Calcium preventing locomotor behavioral and dental toxicities by decreasing serum fluoride level in rats

Environmental Toxicology and Pharmacology

Perumal E. and Paul, V

1. Effects of sodium fluoride on locomotor behavior and a few biochemical parameters in rats

Environmental Toxicology and Pharmacology

Paul, V., Perumal E. and Jayakumar, A. R